No. 5 Salesianum defeated No. 4 Middletown, 49-25, Friday night to advance to the Division I Football Semifinals.

After a back-and-forth first half, Salesianum took control in the second half and never looked back, shocking the Cavaliers who had defeated Sallies in the regular season 34-7.

In the first half, Salesianum recovered a Middletown fumble and later scored on a five-yard run by Andrew Watkins for 7-0 lead after the extra point kick.

The Cavaliers responded with a 22-yard TD pass from quarterback Drew Fry to Nick Johnston to tie the score after the extra-point kick.

After a Salesianum fumble, the Cavs took a 13-7 lead on a 22-yard touchdown run by Najair Smith.

Sallies surged ahead 14-13 on a 50-yard run by Watkins and the extra-point kick.

Middletown retook the lead 19-14 on a touchdown pass from Fry to Esaias Guthrie.

With under a minute left in the second quarter, Salesianum intercepted a pass and later scored on a one-yard run by Watkins for a 21-19 advantage at halftime.

In the third quarter, Salesianum scored when quarterback Gabrielle Puzzangara found Sean Ragan for a 22-yard touchdown completion to go up by nine, 28-19. 

Salesianum added two more sores in the third, a 10-yard Jesse Wheatley rushing score and another touchdown pass from Puzzangara, who hooked up with Cole Mettenheimer for a 31-yard touchdown.

On the next Middletown possession, the Cavs fumbled deep in their own end, leading to five-yard TD from Watkins, putting Salesianum up 49-19.

Fry threw a touchdown pass to Trey Griffin for the final score for Middletown.

With the win Salesianum earns a semifinal matchup next Saturday, Nov. 24 at No. 1 Hodgson at 11 a.m .